Estriol

Estriol is an estrogen hormone that may be prescribed in a compounded cream for certain menopause symptoms. Results vary. Compounded medications are prepared by a licensed pharmacy for one patient and are not FDA-approved. A licensed physician in your state reviews your health history before deciding whether estriol is appropriate.

Estriol vaginal cream may help with vaginal dryness linked to low estrogen after menopause. Results vary. It is not a treatment for every cause of burning, itching, or painful sex. A licensed physician in your state must review your symptoms and decide whether an exam or testing is needed.

Do not assume estriol skin cream will treat hot flashes or improve aging skin. Evidence for these uses of compounded estriol is limited, and results vary. A skin cream is not interchangeable with a vaginal cream. A licensed physician in your state can review your goals and discuss better-studied options.

Estriol can cause local irritation, breast tenderness, headache, or spotting. Risks depend on the formula, dose, and how much hormone reaches the bloodstream. Get emergency help for chest pain, sudden trouble breathing, or stroke symptoms. Report any bleeding after menopause promptly, even if you think estriol caused it.

Estriol needs careful review if you have unexplained vaginal bleeding, a history of hormone-sensitive cancer, blood clots, stroke, or liver disease. Tell your physician if you are pregnant, might be pregnant, or are breastfeeding. A licensed physician in your state decides whether treatment fits your health history and symptoms.

Use estriol only in the amount, location, and schedule listed on your prescription. Vaginal and skin creams have different directions and should not be swapped. Ask your pharmacist to explain the applicator or pump before use. Do not increase your dose or double a missed dose without medical guidance.

Estriol may not fit safely with every hormone, medicine, or vaginal product. Share all prescriptions, over-the-counter medicines, and supplements with your physician. Include cancer treatments and other estrogen products. Ask your pharmacist whether the cream base affects condoms or diaphragms, and do not add progesterone on your own.

Estriol is not an instant lubricant, and there is no guaranteed timeline for relief with a compounded formula. Vaginal estrogen treatment may take several weeks to ease menopause-related symptoms. Results vary. Follow your prescribed schedule and contact your physician if symptoms persist, worsen, or include bleeding, discharge, or pain.

You can discuss stopping estriol or switching treatments with your physician at any time. Do not assume another estrogen product uses the same dose or schedule. Vaginal symptoms may return after treatment stops. Results vary. Your physician can review side effects, your goals, and FDA-approved or nonhormonal alternatives.

To request estriol through Verra Health, complete an online or video visit for physician review. A licensed physician in your state decides whether treatment is appropriate; a prescription is not guaranteed. Medication is charged only after approval. The current medication price is shown on the treatment page.