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Mental health · FAQ

What side effects should I watch for with Bupropion XL 150 mg?

Short answer

Bupropion XL can cause dry mouth, nausea, constipation, headache, trouble sleeping, or feeling restless. It can also raise blood pressure. Less common but serious risks include seizures, severe allergic reactions, and mood changes. Contact your physician about concerning symptoms. Anyone in crisis can call or text 988 for immediate support.

Common side effects of Bupropion XL include dry mouth, nausea, constipation, headache, sweating, trouble sleeping, and feeling anxious or restless. Tell your physician if symptoms bother you or interfere with daily life. Do not change your dose to manage side effects without their advice.

Bupropion can raise blood pressure. Your physician may recommend checking it before and during treatment, especially if you use nicotine replacement products. It can also trigger mania in some people, with signs such as little need for sleep, racing thoughts, or risky behavior.

Get emergency care for a seizure, trouble breathing, or swelling of the face or throat. Serious skin reactions also need urgent medical attention. Contact your physician promptly for unusual behavior, severe agitation, or worsening depression.

Antidepressants can increase suicidal thoughts or behavior in some people, especially younger people early in treatment or after dose changes. Anyone in crisis can call or text 988, the Suicide & Crisis Lifeline. Call 911 if there is immediate danger.

Sources

Written by the Verra clinical team · Medical review pending

General information, not medical advice. If you're in crisis, call or text 988.

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