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Mental health · FAQ

How should I take my daily Bupropion XL 150 mg tablet?

Short answer

Take Bupropion XL exactly as your prescribing physician and label direct, usually one 150 mg tablet each morning. Swallow the tablet whole with water. You may take it with or without food. Do not split, crush, or chew it, and do not change the schedule without medical advice.

Follow your prescribing physician’s instructions and the pharmacy label each time you take Bupropion XL. For this product, the typical directions are one 150 mg tablet each morning. Taking it at a consistent time can help you remember it. Do not change the timing or dose without checking with your physician or pharmacist.

Swallow the tablet whole with water. Do not split, crush, or chew an XL tablet. Its extended-release design controls how the medicine enters your body. Damaging the tablet can release too much medicine at once and raise seizure risk.

You can take it with or without food. If it upsets your stomach, ask your pharmacist about taking it with a meal. Bupropion can cause trouble sleeping, which is one reason morning dosing is often used.

You may notice what looks like a tablet shell in your stool. This can happen with some extended-release tablets and does not mean you should take another dose. Ask your pharmacist if you have questions about your specific tablet.

Sources

Written by the Verra clinical team · Medical review pending

General information, not medical advice. If you're in crisis, call or text 988.

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