Medications · FAQ
What is enclomiphene, and how does it work?
Short answer
Enclomiphene is a selective estrogen receptor modulator, or SERM. It changes estrogen signals to the brain, which can increase signals that tell the testes to make testosterone. Results vary. Enclomiphene is not FDA-approved. A physician must review your symptoms, health history, and lab results before deciding whether it is appropriate.
Enclomiphene is a selective estrogen receptor modulator, often called a SERM. It blocks some estrogen feedback signals to the brain. This can lead the brain to release more of the hormones that tell the testes to make testosterone. Results vary.
Unlike testosterone replacement, enclomiphene does not directly add testosterone to your body. It relies on your own hormone system and testes being able to respond. That is why the cause of low testosterone matters. A low lab result alone is not enough to decide which treatment fits your needs.
Enclomiphene is not FDA-approved for any use. Compounded medications are prepared by a licensed pharmacy for one patient and are not FDA-approved. Their safety and effectiveness are not reviewed by the FDA before they are marketed.
A licensed physician in your state decides whether treatment is appropriate. That review may include your symptoms, morning testosterone tests, other hormone tests, medications, and fertility goals. Follow-up lab testing is needed if treatment is prescribed.
Sources
Written by the Verra clinical team · Medical review pending
General information, not medical advice. If you're in crisis, call or text 988.