Medications · FAQ
Is bupropion less likely than SSRIs to cause sexual side effects?
Short answer
Bupropion is generally less likely than SSRIs to cause sexual side effects, such as lower desire or trouble reaching orgasm. Results vary. Sexual side effects can still happen, and depression itself can affect sexual health. Discuss concerns with your physician rather than changing or stopping your medicine on your own.
Bupropion generally has a lower risk of sexual side effects than SSRIs. These effects can include reduced sexual desire, erection problems, or difficulty reaching orgasm. Results vary. A lower risk does not mean that bupropion cannot cause sexual problems or that switching will resolve them.
Depression, stress, sleep problems, other medicines, and some health conditions can also affect sexual function. Tell your physician when the problem started and whether it changed after starting a medicine or adjusting a dose. This information can help guide a review of possible causes.
A licensed physician in your state may consider bupropion when sexual side effects are a concern, but it is not appropriate for everyone. Seizure risk, eating disorder history, and drug interactions still matter. Do not add bupropion to another antidepressant without medical guidance.
If sexual side effects are affecting your quality of life, bring them up during your visit. Your physician can discuss options and follow-up. Do not skip doses or stop treatment to manage these effects on your own.
Sources
Written by the Verra clinical team · Medical review pending
General information, not medical advice. If you're in crisis, call or text 988.