Mental health · FAQ
How do I switch from another antidepressant to Bupropion XL 150 mg?
Short answer
A licensed physician in your state must review your current treatment before you switch to Bupropion XL. Do not stop, overlap, or replace medicines on your own. Your plan may require a gradual dose change or waiting period. Follow your prescribing physician’s written instructions and the labels for both medicines.
Switching to Bupropion XL requires a plan from a licensed physician in your state. The right approach depends on your current medicine, dose, treatment history, and other health conditions. Share a complete list of medicines and supplements, plus any past problems when starting or stopping antidepressants.
Some medicines need to be reduced slowly. Others require a waiting period before bupropion can begin. MAO inhibitors have specific spacing rules because of serious interaction risks. Do not decide on your own to overlap medicines or stop one suddenly.
Ask for clear written instructions showing when to take each medicine, when to change a dose, and when to contact your physician. Follow the pharmacy labels, and ask your pharmacist to clarify any conflicting directions. Do not split or crush Bupropion XL tablets to make a different dose.
Your physician will monitor symptoms and side effects during the switch. Results vary. Report worsening depression, severe restlessness, or unusual mood changes promptly. Anyone in crisis can call or text 988. Call 911 for immediate danger.
Sources
Written by the Verra clinical team · Medical review pending
General information, not medical advice. If you're in crisis, call or text 988.