Medications · FAQ
What side effects can spironolactone cause?
Short answer
Spironolactone can cause more frequent urination, dizziness, stomach upset, breast tenderness, and irregular periods. It can also raise potassium or affect kidney function. Seek urgent care for fainting, severe weakness, or an irregular heartbeat. Call 911 for trouble breathing or swelling of the face, lips, or tongue.
Common side effects of spironolactone include increased urination, dizziness, headache, stomach upset, breast tenderness, and changes in menstrual bleeding. Some people feel lightheaded when standing up, especially if blood pressure drops. Stand up slowly and avoid driving if you feel dizzy or faint.
More serious concerns include high potassium, dehydration, low blood pressure, and kidney problems. High potassium may cause no clear symptoms. When symptoms occur, they can include muscle weakness, tingling, or an irregular heartbeat. Lab tests may be needed even when you feel well. Seek urgent care for fainting, severe weakness, or a new irregular heartbeat.
Call 911 for trouble breathing or swelling of the face, lips, or tongue. Contact your clinician promptly for much less urination, ongoing vomiting or diarrhea, or a severe rash. Do not try to manage these problems by changing your dose or adding supplements yourself. Let your physician know about side effects that affect daily life so they can review your treatment safely.
Sources
Written by the Verra clinical team · Medical review pending
General information, not medical advice. If you're in crisis, call or text 988.