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Medications · FAQ

What is spironolactone, and how does it work?

Short answer

Spironolactone is a prescription medicine that blocks androgen effects and helps the body remove extra salt and water. It is used for certain heart and blood pressure conditions. It is also used off-label for hormonal acne, female hair thinning, and some PCOS symptoms. Results vary.

Spironolactone has two main actions. It blocks aldosterone, a hormone that affects salt and water balance. This makes it a diuretic, sometimes called a water pill. Unlike some other diuretics, it helps the body keep potassium. It is prescribed for certain heart, blood pressure, and fluid buildup conditions.

It also blocks some effects of androgens. These hormones can play a role in oily skin, acne, unwanted hair growth, and scalp hair thinning. Physicians may prescribe spironolactone off-label for these concerns. Results vary. Off-label means the medicine is prescribed for a use that is not listed in its FDA-approved labeling.

These uses require different care plans. A dose used for one condition may not be right for another. A licensed physician in your state decides whether treatment is appropriate after reviewing your health history, medicines, and pregnancy plans. Kidney problems, high potassium, and certain drug interactions can make spironolactone unsafe. Do not use another person's prescription or change your dose on your own.

Sources

Written by the Verra clinical team · Medical review pending

General information, not medical advice. If you're in crisis, call or text 988.

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