What should I know about compounded medications for erectile dysfunction (ED)?

Compounded medications are prepared by a licensed pharmacy for one patient and are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are marketed. Compounding may meet a patient's specific medical need, but it also carries risks, including possible problems with strength or contamination.

If a compounded ED medicine is prescribed, ask why that option is being recommended. Review its ingredients, dose, dosage form, and directions with your physician or pharmacist. Do not assume that instructions for a standard tablet apply to a compounded product. Timing, storage, and use instructions can differ.

Compounded ED medicines can still cause side effects and serious drug interactions. The warnings for their active ingredients remain important, including restrictions involving nitrates when sildenafil or tadalafil is used. Results vary. Follow the pharmacy label and its beyond-use date. Contact the pharmacy if the packaging is damaged or the directions are unclear. A licensed physician in your state decides whether treatment is appropriate.