Can propranolol interact with alcohol, other medicines, or supplements?

Propranolol can interact with other medicines that slow the heart or lower blood pressure. Examples include verapamil, diltiazem, and some heart rhythm medicines. Certain antidepressants can also change propranolol levels or add to its effects. Your physician or pharmacist should check your full medication list.

Tell them about insulin and other diabetes medicines. Propranolol can mask a fast heartbeat during low blood sugar, making an episode harder to notice. Also mention asthma inhalers, migraine treatments, cold medicines, sleep aids, and supplements. Products bought without a prescription can still cause problems.

Alcohol can increase dizziness and add to the blood-pressure-lowering effect. It is safest to avoid alcohol until you have discussed your situation with your physician and know how propranolol affects you. Do not use alcohol as a way to manage performance anxiety.

Do not stop another prescribed medicine to make room for propranolol. Ask for an interaction check whenever you start, stop, or change any medicine, even if you take propranolol only occasionally.