Semaglutide vs tirzepatide: Who may qualify for weight management treatment?

Approved adult weight management products generally are intended for people with a body mass index, or BMI, of 30 or higher. They may also be used at a BMI of 27 or higher when a person has a weight-related condition, such as high blood pressure or type 2 diabetes. Meeting a BMI cutoff does not mean a prescription is appropriate.

Both drugs have important limits. They should not be used by people with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2, also called MEN 2. A past serious allergic reaction to the drug is another reason not to use it.

Tell your physician about pancreatitis, gallbladder disease, severe stomach-emptying problems, kidney concerns, or diabetic eye disease. These issues may affect the choice or require closer review.

Pregnancy, plans for pregnancy, and breastfeeding also need discussion. At Verra, a physician licensed in your state reviews these details and decides whether either treatment is appropriate for you.