How is injectable semaglutide taken and increased over time?

Injectable semaglutide is generally given under the skin of the abdomen, thigh, or upper arm once weekly. Rotate injection sites and follow the directions supplied with your product. Your starting dose and later increases depend on the exact medication, your health needs, and how well you tolerate treatment.

Doses are usually raised in steps rather than started at the highest dose. Your physician may delay an increase if you have side effects. Taking more than prescribed can cause serious illness. A licensed physician in your state decides which dosing plan is appropriate for you.

If you receive a vial, ask the pharmacy to explain the dose in milligrams and the matching volume for your syringe. Syringe units are not milligrams. Different concentrations can require different volumes, even when the prescribed dose is unchanged. Compounded medications are prepared by a licensed pharmacy for one patient and are not FDA-approved.

Do not inject a dose if the label or instructions are unclear. Contact the pharmacy or prescribing team first. Never use a dosing chart from social media or another patient.